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Multiple sclerosis (MS) is the most common acquired neurological disorder of young adults globally, with the typical patient with MS being a young woman at reproductive age. The disease shows a female predominance that is now approximately 3 to 1, and this gender bias is expected to become more pronounced with MS on the rise in young women. Between 2006 and 2014 in North America, pregnancy rates in women with MS increased significantly while pregnancy rates in general declined (Figure 1). This suggests that clinicians are becoming more comfortable managing the complex reciprocal effects of MS and pregnancy, and that significant efforts among MS specialists to educate the public and genera