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Multiple sclerosis (MS) is typically diagnosed in women during childbearing age and is twice more frequent in females than in males, therefore, women with MS may face several pregnancy-related issues, including concerns regarding the effects of medications commonly used in MS treatment [Ghezzi et al, 2013]. Choosing the right approach to treatment during pregnancy is consequently a key consideration for women with MS.

Most disease-modifying therapies (DMTs) are contraindicated during pregnancy and most women are advised to stop using them when planning for, and during a pregnancy, unless the balance between benefit and risk favours treatment continuation. However, in the case of a severe relapse during pregnancy, female patients could be treated with a short, high dose of a corticosteroid such as methylprednisolone to speed up recovery, although this should generally be limited to disabling relapses [Miller et al, 2014].

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